Pathophysiology

Pathophysiology of PNH

The complications from PNH are devastating and systemic. The pathophysiology behind these complications, while complement-mediated, is multifactorial in nature.1-5

Doctor Goldberg video

Watch Jack Goldberg, MD, discuss the limitations of anticoagulation therapy in treating thrombosis in PNH.

Clinical Assessment for Risks of Early Mortality

For more information about the important role of a full clinical assessment for your patient with PNH, download the Clinical Assessment for Risks of Early Mortality.

Thromboembolism

PNH has been called “the most vicious acquired thrombophilic state known in medicine”.17 Learn which common symptoms are associated with an increased risk of thromboembolism in a patient diagnosed with PNH.

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