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Learn About Paroxysmal Nocturnal Hemoglobinuria (PNH)


Start Learning—and Change the Way You See PNH

  • PNH is serious. It starts with your blood, but it can affect your entire body
  • PNH is dangerous. If you don’t take care of PNH, it can lead to serious health problems, including some that can be life-threatening
  • PNH is constant. Even though you can’t see it, hemolysis is always happening
  • PNH is manageable. Speak with your doctor to find out what’s right for you

If left unaddressed, PNH can lead to:

  • Blood clots can block veins and arteries and lead to heart attack , stroke , and organ damage, as well as other problems
  • Chronic kidney disease occurs in almost 2/3 of people with PNH
  • Lung problems occur in almost 1/2 of patients with PNH. They can be caused by pulmonary hypertension . This can lead to shortness of breath and other serious health problems
  • Fatigue due to hemolysis. Hemolysis affects the way oxygen gets delivered throughout your body. This can make you feel weak and tired to the point where once-normal, everyday activities become a struggle

Click on a word that is underlined with a light dotted line and an explanation of that word will appear.

Hear Victor, an actual PNH patient, discuss how he learned he had PNH.

Listen as Dr. Charles M. Farber, a specialist of blood and blood diseases, explains how blood clots affect someone with PNH.

Watch Scott, a PNH patient, talk about being proactive with his disease.

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